Product Data Sheet

Bromo-PEG1-C2-azide

Catalog No. A82100

main product photo
Bromo-PEG1-C2-azide is a PEG-based linker designed for the synthesis of PROTACs, targeting protein degradation pathways. This compound features an azide functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkynyl compounds. Additionally, it can perform strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN entities, making it a versatile tool in chemical biology for developing protein-targeting therapeutic agents.
Chemical Information
Catalog NumA82100
M. Wt194.03
FormulaC4H8BrN3O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1144106-65-9
Synonyms
SMILESBrCCOCCN=[N+]=[N-]
Biological Activity
DescriptionBromo-PEG1-C2-azide is a PEG-based linker designed for the synthesis of PROTACs, targeting protein degradation pathways. This compound features an azide functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkynyl compounds. Additionally, it can perform strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN entities, making it a versatile tool in chemical biology for developing protein-targeting therapeutic agents.
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