Product Data Sheet
Azido-PEG4-Thiol
Catalog No. A82173
Azido-PEG4-Thiol is a PEG-based linker designed specifically for PROTAC (Proteolysis Targeting Chimera) synthesis. Functioning through click chemistry, it features an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, Azido-PEG4-Thiol can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) with compounds bearing DBCO or BCN groups. This compound serves as a valuable tool in the development of targeted protein degradation strategies in chemical biology research.
Chemical Information
| Catalog Num | A82173 |
|---|---|
| M. Wt | 279.36 |
| Formula | C10H21N3O4S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2720615-82-5 |
| Synonyms | |
| SMILES | SCCOCCOCCOCCOCCN=[N+]=[N-] |
Biological Activity
| Description | Azido-PEG4-Thiol is a PEG-based linker designed specifically for PROTAC (Proteolysis Targeting Chimera) synthesis. Functioning through click chemistry, it features an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, Azido-PEG4-Thiol can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) with compounds bearing DBCO or BCN groups. This compound serves as a valuable tool in the development of targeted protein degradation strategies in chemical biology research. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
