Product Data Sheet

N-DBCO-N-bis(PEG2-C2-acid)

Catalog No. A82177

main product photo
N-DBCO-N-bis(PEG2-C2-acid) is a PEG-based linker designed for PROTAC synthesis, functioning primarily through click chemistry. Featuring a DBCO moiety, it facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing compounds. This reagent enhances the development of targeted protein degradation strategies, proving valuable in various biochemical applications and studies aimed at modulating protein levels within cellular systems.
Chemical Information
Catalog NumA82177
M. Wt624.68
FormulaC33H40N2O10
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2110449-00-6
Synonyms
SMILESO=C(N1C2=CC=CC=C2C#CC3=CC=CC=C3C1)CCC(N(CCOCCOCCC(O)=O)CCOCCOCCC(O)=O)=O
Biological Activity
DescriptionN-DBCO-N-bis(PEG2-C2-acid) is a PEG-based linker designed for PROTAC synthesis, functioning primarily through click chemistry. Featuring a DBCO moiety, it facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing compounds. This reagent enhances the development of targeted protein degradation strategies, proving valuable in various biochemical applications and studies aimed at modulating protein levels within cellular systems.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.