Product Data Sheet

Azido-PEG1-PFP ester

Catalog No. A82351

main product photo
Azido-PEG1-PFP ester is a PEG-based PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound features an azide functional group that allows for copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, Azido-PEG1-PFP ester can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN-modified compounds, facilitating targeted protein degradation studies in chemical biology research.
Chemical Information
Catalog NumA82351
M. Wt325.19
FormulaC11H8F5N3O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1807505-32-3
Synonyms
SMILESO=C(OC1=C(F)C(F)=C(F)C(F)=C1F)CCOCCN=[N+]=[N-]
Biological Activity
DescriptionAzido-PEG1-PFP ester is a PEG-based PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound features an azide functional group that allows for copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, Azido-PEG1-PFP ester can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN-modified compounds, facilitating targeted protein degradation studies in chemical biology research.
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SHIPPING AND STORAGE
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