Product Data Sheet
PC DBCO-PEG4-NHS ester
Catalog No. A82355
PC DBCO-PEG4-NHS ester is a PEG-based linker designed for use in the synthesis of PROTACs, functioning as a critical component in targeted protein degradation. This compound features a DBCO moiety that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-functionalized molecules. It serves as a valuable tool in chemical biology for developing novel therapeutic strategies by enabling the creation of bifunctional compounds that can modulate protein interactions.
Chemical Information
| Catalog Num | A82355 |
|---|---|
| M. Wt | 945.96 |
| Formula | C47H55N5O16 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2055025-02-8 |
| Synonyms | |
| SMILES | [O-][N+](C(C(C(OC(ON1C(CCC1=O)=O)=O)C)=C2)=CC(OCCCC(NCCOCCOCCOCCOCCC(NCCC(N3CC4=C(C=CC=C4)C#CC5=C3C=CC=C5)=O)=O)=O)=C2OC)=O |
Biological Activity
| Description | PC DBCO-PEG4-NHS ester is a PEG-based linker designed for use in the synthesis of PROTACs, functioning as a critical component in targeted protein degradation. This compound features a DBCO moiety that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-functionalized molecules. It serves as a valuable tool in chemical biology for developing novel therapeutic strategies by enabling the creation of bifunctional compounds that can modulate protein interactions. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
