Product Data Sheet
Azido-PEG3-chloroacetamide
Catalog No. A82367
Azido-PEG3-chloroacetamide is a PEG-based linker designed for use in the synthesis of proteolysis-targeting chimeras (PROTACs). This compound features an azide functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions with alkyne-containing molecules. Additionally, it can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with entities bearing DBCO or BCN groups, facilitating the assembly of complex PROTACs for targeted protein degradation studies.
Chemical Information
| Catalog Num | A82367 |
|---|---|
| M. Wt | 294.74 |
| Formula | C10H19ClN4O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 604766-23-6 |
| Synonyms | |
| SMILES | O=C(NCCOCCOCCOCCN=[N+]=[N-])CCl |
Biological Activity
| Description | Azido-PEG3-chloroacetamide is a PEG-based linker designed for use in the synthesis of proteolysis-targeting chimeras (PROTACs). This compound features an azide functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions with alkyne-containing molecules. Additionally, it can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with entities bearing DBCO or BCN groups, facilitating the assembly of complex PROTACs for targeted protein degradation studies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
