Product Data Sheet

m-PEG2-azide

Catalog No. A82372

main product photo
m-PEG2-azide is a PEG-based PROTAC linker designed for the synthesis of PROTACs. It features an azide functional group, facilitating copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-bearing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN-modified compounds, making it a versatile tool for the development of targeted protein degradation strategies. Its applications are essential for advancing research in protein modulation and therapeutic development.
Chemical Information
Catalog NumA82372
M. Wt145.16
FormulaC5H11N3O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.215181-61-6
Synonyms
SMILESCOCCOCCN=[N+]=[N-]
Biological Activity
Descriptionm-PEG2-azide is a PEG-based PROTAC linker designed for the synthesis of PROTACs. It features an azide functional group, facilitating copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-bearing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN-modified compounds, making it a versatile tool for the development of targeted protein degradation strategies. Its applications are essential for advancing research in protein modulation and therapeutic development.
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