Product Data Sheet
Bis-PEG4-PFP ester
Catalog No. A82393
Bis-PEG4-PFP ester is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of PROTAC (Proteolysis Targeting Chimeras) molecules. This compound facilitates the effective conjugation of target proteins to E3 ligases, enhancing protein degradation through the ubiquitin-proteasome system. Its versatile application in chemical biology makes it an essential tool for researchers exploring targeted protein degradation and therapeutic development.
Chemical Information
| Catalog Num | A82393 |
|---|---|
| M. Wt | 626.39 |
| Formula | C24H20F10O8 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1314378-12-5 |
| Synonyms | |
| SMILES | O=C(OC1=C(F)C(F)=C(F)C(F)=C1F)CCOCCOCCOCCOCCC(OC2=C(F)C(F)=C(F)C(F)=C2F)=O |
Biological Activity
| Description | Bis-PEG4-PFP ester is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of PROTAC (Proteolysis Targeting Chimeras) molecules. This compound facilitates the effective conjugation of target proteins to E3 ligases, enhancing protein degradation through the ubiquitin-proteasome system. Its versatile application in chemical biology makes it an essential tool for researchers exploring targeted protein degradation and therapeutic development. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
