Product Data Sheet
Azido-PEG5-PFP ester
Catalog No. A82417
Azido-PEG5-PFP ester serves as a versatile PROTAC linker featuring a polyethylene glycol (PEG) moiety. Its primary mechanism involves facilitating targeted protein degradation via a biocompatible linker design. This compound is suitable for the synthesis of PROTACs, enabling efficient conjugation through click chemistry techniques, including copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN-containing molecules. Its application in research supports advancements in targeted therapeutics and protein modulation.
Chemical Information
| Catalog Num | A82417 |
|---|---|
| M. Wt | 501.40 |
| Formula | C19H24F5N3O7 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1818294-48-2 |
| Synonyms | |
| SMILES | O=C(OC1=C(F)C(F)=C(F)C(F)=C1F)CCOCCOCCOCCOCCOCCN=[N+]=[N-] |
Biological Activity
| Description | Azido-PEG5-PFP ester serves as a versatile PROTAC linker featuring a polyethylene glycol (PEG) moiety. Its primary mechanism involves facilitating targeted protein degradation via a biocompatible linker design. This compound is suitable for the synthesis of PROTACs, enabling efficient conjugation through click chemistry techniques, including copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN-containing molecules. Its application in research supports advancements in targeted therapeutics and protein modulation. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
