Product Data Sheet
DBCO-PEG1-acid
Catalog No. A82619
DBCO-PEG1-acid is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). Featuring a DBCO moiety, this compound facilitates efficient click chemistry through strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing substrates. DBCO-PEG1-acid is integral for developing targeted degradation strategies in protein research, enabling precise modulation of protein levels for various biological applications.
Chemical Information
| Catalog Num | A82619 |
|---|---|
| M. Wt | 420.46 |
| Formula | C24H24N2O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2228857-38-1 |
| Synonyms | |
| SMILES | O=C(N1CC2=C(C#CC3=C1C=CC=C3)C=CC=C2)CCC(NCCOCCC(O)=O)=O |
Biological Activity
| Description | DBCO-PEG1-acid is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). Featuring a DBCO moiety, this compound facilitates efficient click chemistry through strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing substrates. DBCO-PEG1-acid is integral for developing targeted degradation strategies in protein research, enabling precise modulation of protein levels for various biological applications. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
