Product Data Sheet

N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid

Catalog No. A82631

main product photo
N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid is a PEG-based linker designed for use in the synthesis of PROTACs. This compound features an azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN-containing compounds, making it a versatile tool for targeted protein degradation research applications.
Chemical Information
Catalog NumA82631
M. Wt681.77
FormulaC29H55N5O13
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2183440-74-4
Synonyms
SMILESO=C(OC(C)(C)C)NCCOCCOCCC(N(CCOCCOCCOCCN=[N+]=[N-])CCOCCOCCOCCC(O)=O)=O
Biological Activity
DescriptionN-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid is a PEG-based linker designed for use in the synthesis of PROTACs. This compound features an azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN-containing compounds, making it a versatile tool for targeted protein degradation research applications.
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SHIPPING AND STORAGE
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