Product Data Sheet
Amino-PEG11-amine
Catalog No. A82641
Amino-PEG11-amine is a PEG-based linker designed for use in PROTAC (Proteolysis Targeting Chimeras) applications. This 11-unit polyethylene glycol (PEG) moiety facilitates the conjugation of two mono diethylstilbestrol (DES)-based ligands, offering a novel approach to enhance the selectivity and potency of estrogen receptor (ER) antagonists. It is particularly relevant for research focused on developing targeted therapies for breast cancer through improved endocrine resistance mechanisms.
Chemical Information
| Catalog Num | A82641 |
|---|---|
| M. Wt | 544.68 |
| Formula | C24H52N2O11 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 479200-82-3 |
| Synonyms | |
| SMILES | NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN |
Biological Activity
| Description | Amino-PEG11-amine is a PEG-based linker designed for use in PROTAC (Proteolysis Targeting Chimeras) applications. This 11-unit polyethylene glycol (PEG) moiety facilitates the conjugation of two mono diethylstilbestrol (DES)-based ligands, offering a novel approach to enhance the selectivity and potency of estrogen receptor (ER) antagonists. It is particularly relevant for research focused on developing targeted therapies for breast cancer through improved endocrine resistance mechanisms. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
