Product Data Sheet
Cbz-PEG2-bromide
Catalog No. A82685
Cbz-PEG2-bromide is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis-Targeting Chimeras). This compound facilitates targeted protein degradation by covalently linking E3 ligases and the protein of interest, thereby promoting the ubiquitination and subsequent proteasomal degradation of specific proteins. It is a valuable tool in drug discovery and chemical biology for the development of new therapeutics targeting challenging proteins.
Chemical Information
| Catalog Num | A82685 |
|---|---|
| M. Wt | 346.22 |
| Formula | C14H20BrNO4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2100283-00-7 |
| Synonyms | |
| SMILES | O=C(NCCOCCOCCBr)OCC1=CC=CC=C1 |
Biological Activity
| Description | Cbz-PEG2-bromide is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis-Targeting Chimeras). This compound facilitates targeted protein degradation by covalently linking E3 ligases and the protein of interest, thereby promoting the ubiquitination and subsequent proteasomal degradation of specific proteins. It is a valuable tool in drug discovery and chemical biology for the development of new therapeutics targeting challenging proteins. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
