Product Data Sheet

Azido-PEG8-PFP ester

Catalog No. A82743

main product photo
Azido-PEG8-PFP ester serves as a PEG-based PROTAC linker and is integral to the synthesis of PROTACs. This compound features an azide group that enables it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN-functionalized compounds, making it versatile for constructing targeted protein degradation systems in chemical biology research applications.
Chemical Information
Catalog NumA82743
M. Wt633.56
FormulaC25H36F5N3O10
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2055014-62-3
Synonyms
SMILESO=C(OC1=C(F)C(F)=C(F)C(F)=C1F)CCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]
Biological Activity
DescriptionAzido-PEG8-PFP ester serves as a PEG-based PROTAC linker and is integral to the synthesis of PROTACs. This compound features an azide group that enables it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN-functionalized compounds, making it versatile for constructing targeted protein degradation systems in chemical biology research applications.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.