Product Data Sheet
HOCH2-Cyclobutane-CH2COOMe
Catalog No. A82852
HOCH2-Cyclobutane-CH2COOMe is a versatile PROTAC linker that facilitates the creation of targeted protein degradation bioconjugates. This compound aids in the design of PROTACs (proteolysis-targeting chimeras) by connecting a target protein ligand to an E3 ligase recruitor, enhancing the efficiency of selective protein degradation. Its unique cyclobutane structure contributes to improved stability and cell permeability, making it suitable for various applications in chemical biology and drug discovery.
Chemical Information
| Catalog Num | A82852 |
|---|---|
| M. Wt | 158.20 |
| Formula | C8H14O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1114554-24-3 |
| Synonyms | |
| SMILES | O=C(OC)CC1CC(CO)C1 |
Biological Activity
| Description | HOCH2-Cyclobutane-CH2COOMe is a versatile PROTAC linker that facilitates the creation of targeted protein degradation bioconjugates. This compound aids in the design of PROTACs (proteolysis-targeting chimeras) by connecting a target protein ligand to an E3 ligase recruitor, enhancing the efficiency of selective protein degradation. Its unique cyclobutane structure contributes to improved stability and cell permeability, making it suitable for various applications in chemical biology and drug discovery. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
