Product Data Sheet
5-Ethynyl-2'-deoxyuridine-13C
Catalog No. A82964
5-Ethynyl-2'-deoxyuridine-13C is a stable isotope-labeled analogue of 5-Ethynyl-2'-deoxyuridine (EdU), targeting cellular DNA during replication. This compound is incorporated into DNA and allows for visualization through a copper-catalyzed azide-alkyne cycloaddition (CuAAc) in Click chemistry applications. EdU-13C serves as a sensitive and efficient probe for assessing cell proliferation, making it invaluable for research in cell biology and drug development. Additionally, it can function as a linker in the synthesis of PROTACs, facilitating studies in targeted protein degradation.
Chemical Information
| Catalog Num | A82964 |
|---|---|
| M. Wt | 253.22 |
| Formula | C1013CH12N2O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1610530-40-9 |
| Synonyms | EdU-13C |
| SMILES | O[C@H]1C[C@H](N2C(NC(C([13C]#C)=C2)=O)=O)O[C@@H]1CO |
Biological Activity
| Description | 5-Ethynyl-2'-deoxyuridine-13C is a stable isotope-labeled analogue of 5-Ethynyl-2'-deoxyuridine (EdU), targeting cellular DNA during replication. This compound is incorporated into DNA and allows for visualization through a copper-catalyzed azide-alkyne cycloaddition (CuAAc) in Click chemistry applications. EdU-13C serves as a sensitive and efficient probe for assessing cell proliferation, making it invaluable for research in cell biology and drug development. Additionally, it can function as a linker in the synthesis of PROTACs, facilitating studies in targeted protein degradation. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
