Azide-PEG3-L-alanine-Fmoc
Catalog No. A82988

Azide-PEG3-L-alanine-Fmoc is a PEG-based PROTAC linker that facilitates the synthesis of PROTACs through its azide functionality. This compound is capable of participating in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules and can also engage in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN-modified compounds. Its unique properties make it a valuable tool for researchers working on targeted protein degradation and related applications in chemical biology.
Chemical Information
| Catalog Num | A82988 |
|---|---|
| M. Wt | 484.50 |
| Formula | C24H28N4O7 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2054345-69-4 |
| Synonyms | |
| SMILES | O=C(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)N[C@@H](C(O)=O)COCCOCCOCCN=[N+]=[N-] |
Biological Activity
| Description | Azide-PEG3-L-alanine-Fmoc is a PEG-based PROTAC linker that facilitates the synthesis of PROTACs through its azide functionality. This compound is capable of participating in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules and can also engage in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN-modified compounds. Its unique properties make it a valuable tool for researchers working on targeted protein degradation and related applications in chemical biology. |
|---|
RETURN POLICY
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


