Product Data Sheet
SCO-PEG8-COOH
Catalog No. A82992
SCO-PEG8-COOH is a PROTAC linker that facilitates the formation of targeted protein degraders by connecting target proteins to E3 ligases. This polyethylene glycol (PEG) derivative features a maleimide moiety for conjugation with amino groups, particularly lysine residues, enhancing the specificity and efficiency of protein interactions. Its versatility in modifying biomolecules makes it a valuable tool for studies in targeted protein degradation and therapeutic development in chemical biology.
Chemical Information
| Catalog Num | A82992 |
|---|---|
| M. Wt | 591.69 |
| Formula | C28H49NO12 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2143968-79-8 |
| Synonyms | |
| SMILES | O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(OC1C#CCCCCC1)=O)O |
Biological Activity
| Description | SCO-PEG8-COOH is a PROTAC linker that facilitates the formation of targeted protein degraders by connecting target proteins to E3 ligases. This polyethylene glycol (PEG) derivative features a maleimide moiety for conjugation with amino groups, particularly lysine residues, enhancing the specificity and efficiency of protein interactions. Its versatility in modifying biomolecules makes it a valuable tool for studies in targeted protein degradation and therapeutic development in chemical biology. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
