Product Data Sheet
Boc-NH-C3-O-Ph(NO2)-methylester-O-pyrrolidine-2,5-dione
Catalog No. A83023
Boc-NH-C3-O-Ph(NO2)-methylester-O-pyrrolidine-2,5-dione is a versatile linker designed for the synthesis of PROTACs, specifically utilized in the development of BRD4 Degrader-26. This compound enables the assembly of targeted protein degraders, facilitating the selective ubiquitination and subsequent degradation of BRD4 protein. Its application in chemical biology research supports the exploration of targeted therapies and novel approaches to modulate protein levels in various disease contexts.
Chemical Information
| Catalog Num | A83023 |
|---|---|
| M. Wt | 467.43 |
| Formula | C20H25N3O10 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3050769-33-7 |
| Synonyms | |
| SMILES | O=[N+]([O-])C(C=C1)=C(COC(ON2C(CCC2=O)=O)=O)C=C1OCCCNC(OC(C)(C)C)=O |
Biological Activity
| Description | Boc-NH-C3-O-Ph(NO2)-methylester-O-pyrrolidine-2,5-dione is a versatile linker designed for the synthesis of PROTACs, specifically utilized in the development of BRD4 Degrader-26. This compound enables the assembly of targeted protein degraders, facilitating the selective ubiquitination and subsequent degradation of BRD4 protein. Its application in chemical biology research supports the exploration of targeted therapies and novel approaches to modulate protein levels in various disease contexts. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
