Product Data Sheet

N-(Azido-PEG2)-N-bis(PEG4-Boc)

Catalog No. A83041

main product photo
N-(Azido-PEG2)-N-bis(PEG4-Boc) is a PEG-based linker designed for use in the synthesis of proteolysis-targeting chimeras (PROTACs). This compound features an azide group that enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups. It provides a versatile approach for researchers developing PROTACs, facilitating targeted protein degradation in various biological applications.
Chemical Information
Catalog NumA83041
M. Wt782.96
FormulaC36H70N4O14
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2112731-81-2
Synonyms
SMILESO=C(CCOCCOCCOCCOCCN(CCOCCOCCOCCOCCC(OC(C)(C)C)=O)CCOCCOCCN=[N+]=[N-])OC(C)(C)C
Biological Activity
DescriptionN-(Azido-PEG2)-N-bis(PEG4-Boc) is a PEG-based linker designed for use in the synthesis of proteolysis-targeting chimeras (PROTACs). This compound features an azide group that enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups. It provides a versatile approach for researchers developing PROTACs, facilitating targeted protein degradation in various biological applications.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.