Product Data Sheet
Phthalimide-PEG3-C2-OTs
Catalog No. A83075
Phthalimide-PEG3-C2-OTs is a PROTAC linker designed to facilitate the synthesis of proteolysis-targeting chimeras (PROTACs). This compound features a phthalimide moiety connected by a polyethylene glycol (PEG) chain, enabling effective linkage between ligands that bind to E3 ubiquitin ligases and target proteins. By harnessing the ubiquitin-proteasome system, PROTACs equipped with Phthalimide-PEG3-C2-OTs promote selective degradation of specific proteins, making it a valuable tool for targeted protein modulation in various biological research applications.
Chemical Information
| Catalog Num | A83075 |
|---|---|
| M. Wt | 477.53 |
| Formula | C23H27NO8S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 382162-12-1 |
| Synonyms | |
| SMILES | CC(C=C1)=CC=C1S(=O)(OCCOCCOCCOCCN2C(C3=C(C=CC=C3)C2=O)=O)=O |
Biological Activity
| Description | Phthalimide-PEG3-C2-OTs is a PROTAC linker designed to facilitate the synthesis of proteolysis-targeting chimeras (PROTACs). This compound features a phthalimide moiety connected by a polyethylene glycol (PEG) chain, enabling effective linkage between ligands that bind to E3 ubiquitin ligases and target proteins. By harnessing the ubiquitin-proteasome system, PROTACs equipped with Phthalimide-PEG3-C2-OTs promote selective degradation of specific proteins, making it a valuable tool for targeted protein modulation in various biological research applications. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
