Product Data Sheet

Propargyl-PEG4-CH2-acid

Catalog No. A83147

main product photo
Propargyl-PEG4-CH2-acid is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound features an alkyne group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with azide-containing molecules. Its application in PROTAC development facilitates targeted protein degradation, making it a valuable tool in chemical biology research and drug discovery efforts.
Chemical Information
Catalog NumA83147
M. Wt274.31
FormulaC13H22O6
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1872433-74-3
Synonyms
SMILESC#CCOCCOCCOCCOCCCC(O)=O
Biological Activity
DescriptionPropargyl-PEG4-CH2-acid is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound features an alkyne group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with azide-containing molecules. Its application in PROTAC development facilitates targeted protein degradation, making it a valuable tool in chemical biology research and drug discovery efforts.
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