Product Data Sheet

Folate-PEG3-alkyne

Catalog No. A83155

main product photo
Folate-PEG3-alkyne is a PEG-based PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound features an alkyne functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with azide-containing molecules. Folate-PEG3-alkyne is essential for developing targeted therapeutic strategies in chemical biology and drug discovery.
Chemical Information
Catalog NumA83155
M. Wt610.62
FormulaC28H34N8O8
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1245285-73-7
Synonyms
SMILESNC(NC1=O)=NC2=C1N=C(C=N2)CNC3=CC=C(C(N[C@@H](CCC(NCCOCCOCCOCC#C)=O)C(O)=O)=O)C=C3
Biological Activity
DescriptionFolate-PEG3-alkyne is a PEG-based PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound features an alkyne functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with azide-containing molecules. Folate-PEG3-alkyne is essential for developing targeted therapeutic strategies in chemical biology and drug discovery.
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SHIPPING AND STORAGE
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