Product Data Sheet
PEG4-bis(phosphonic acid diethyl ester)
Catalog No. A83212
PEG4-bis(phosphonic acid diethyl ester) is a PEG-based linker specifically designed for PROTAC (Proteolysis Targeting Chimera) applications. Its primary mechanism involves facilitating the conjugation of targeting moieties to E3 ligases, enhancing the proteolytic degradation of target proteins. This compound is instrumental in the development of innovative therapeutics through targeted protein degradation strategies, making it an essential reagent for research in drug discovery and cellular mechanisms.
Chemical Information
| Catalog Num | A83212 |
|---|---|
| M. Wt | 466.40 |
| Formula | C16H36O11P2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 106338-06-1 |
| Synonyms | |
| SMILES | O=P(OCC)(OCC)OCCOCCOCCOCCOP(OCC)(OCC)=O |
Biological Activity
| Description | PEG4-bis(phosphonic acid diethyl ester) is a PEG-based linker specifically designed for PROTAC (Proteolysis Targeting Chimera) applications. Its primary mechanism involves facilitating the conjugation of targeting moieties to E3 ligases, enhancing the proteolytic degradation of target proteins. This compound is instrumental in the development of innovative therapeutics through targeted protein degradation strategies, making it an essential reagent for research in drug discovery and cellular mechanisms. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
