Product Data Sheet
SCO-PEG4-COOH
Catalog No. A83287
SCO-PEG4-COOH is a PROTAC linker that facilitates targeted degradation of proteins via the ubiquitin-proteasome system. This compound features a synthetic PEG (polyethylene glycol) spacer, enabling efficient conjugation with amino groups while its SCO moiety is designed to react selectively with amino acid residues, particularly lysine, in proteins or peptides. It is widely utilized in the development of bifunctional compounds and the study of protein interactions within cellular environments. Its biocompatibility and versatility make it a valuable tool for chemical biology and therapeutic research applications.
Chemical Information
| Catalog Num | A83287 |
|---|---|
| M. Wt | 415.48 |
| Formula | C20H33NO8 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2141976-27-2 |
| Synonyms | |
| SMILES | O=C(CCOCCOCCOCCOCCNC(OC1C#CCCCCC1)=O)O |
Biological Activity
| Description | SCO-PEG4-COOH is a PROTAC linker that facilitates targeted degradation of proteins via the ubiquitin-proteasome system. This compound features a synthetic PEG (polyethylene glycol) spacer, enabling efficient conjugation with amino groups while its SCO moiety is designed to react selectively with amino acid residues, particularly lysine, in proteins or peptides. It is widely utilized in the development of bifunctional compounds and the study of protein interactions within cellular environments. Its biocompatibility and versatility make it a valuable tool for chemical biology and therapeutic research applications. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
