Product Data Sheet
Methyltetrazine-PEG24-amine
Catalog No. A83319
Methyltetrazine-PEG24-amine is a polyethylene glycol (PEG) linker designed for use in the synthesis of PROTAC (proteolysis-targeting chimeras). Its primary mechanism involves facilitating the conjugation of target proteins with E3 ligases, enabling targeted protein degradation. This compound is critical for researchers developing novel therapeutic strategies that leverage the ubiquitin-proteasome system to selectively eliminate unwanted proteins. Its biocompatibility and versatility make it a valuable tool in drug discovery and development.
Chemical Information
| Catalog Num | A83319 |
|---|---|
| M. Wt | 1244.50 |
| Formula | C57H105N5O24 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2353410-18-9 |
| Synonyms | |
| SMILES | CC(N=N1)=NN=C1C2=CC=C(OCCOCCN)C=C2.[23] |
Biological Activity
| Description | Methyltetrazine-PEG24-amine is a polyethylene glycol (PEG) linker designed for use in the synthesis of PROTAC (proteolysis-targeting chimeras). Its primary mechanism involves facilitating the conjugation of target proteins with E3 ligases, enabling targeted protein degradation. This compound is critical for researchers developing novel therapeutic strategies that leverage the ubiquitin-proteasome system to selectively eliminate unwanted proteins. Its biocompatibility and versatility make it a valuable tool in drug discovery and development. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
