Product Data Sheet
Mal-PEG2-PFP ester
Catalog No. A83333
Mal-PEG2-PFP ester is a bifunctional linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This alkyl/ether-based compound facilitates the conjugation of target proteins to E3 ligases, enabling selective degradation of proteins of interest through the ubiquitin-proteasome pathway. Its tunable spacer length and functional groups enhance the efficiency and specificity of PROTAC development, making it a valuable tool in chemical biology and drug discovery research.
Chemical Information
| Catalog Num | A83333 |
|---|---|
| M. Wt | 423.29 |
| Formula | C17H14F5NO6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1807512-47-5 |
| Synonyms | |
| SMILES | O=C(OC1=C(F)C(F)=C(F)C(F)=C1F)CCOCCOCCN2C(C=CC2=O)=O |
Biological Activity
| Description | Mal-PEG2-PFP ester is a bifunctional linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This alkyl/ether-based compound facilitates the conjugation of target proteins to E3 ligases, enabling selective degradation of proteins of interest through the ubiquitin-proteasome pathway. Its tunable spacer length and functional groups enhance the efficiency and specificity of PROTAC development, making it a valuable tool in chemical biology and drug discovery research. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
