Product Data Sheet

Boc-NH-PEG8-propargyl

Catalog No. A83346

main product photo
Boc-NH-PEG8-propargyl is a PEG-based linker designed for the synthesis of PROTACs, primarily functioning as a key component in targeted protein degradation. This compound features an alkyne group that enables its application in click chemistry through copper-catalyzed azide-alkyne cycloaddition (CuAAc), facilitating the conjugation of azide-containing molecules. Its utility makes it a valuable tool in medicinal chemistry, particularly for enhancing the specificity and efficiency of PROTAC design and development.
Chemical Information
Catalog NumA83346
M. Wt507.61
FormulaC24H45NO10
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2183440-31-3
Synonyms
SMILESC#CCOCCOCCOCCOCCOCCOCCOCCOCCNC(OC(C)(C)C)=O
Biological Activity
DescriptionBoc-NH-PEG8-propargyl is a PEG-based linker designed for the synthesis of PROTACs, primarily functioning as a key component in targeted protein degradation. This compound features an alkyne group that enables its application in click chemistry through copper-catalyzed azide-alkyne cycloaddition (CuAAc), facilitating the conjugation of azide-containing molecules. Its utility makes it a valuable tool in medicinal chemistry, particularly for enhancing the specificity and efficiency of PROTAC design and development.
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SHIPPING AND STORAGE
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