Product Data Sheet

N-(m-PEG4)-N'-(azide-PEG4)-Cy7

Catalog No. A83372

main product photo
N-(m-PEG4)-N'-(azide-PEG4)-Cy7 is a PEG-based linker designed for use in PROTAC (proteolysis targeting chimeras) synthesis. This compound features an azide functional group, allowing it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing partners, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups. Its biological activity in forming stable linkages facilitates targeted proteolysis research applications, making it a valuable tool for molecular biology and drug development studies.
Chemical Information
Catalog NumA83372
M. Wt852.50
FormulaC46H66ClN5O8
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2107273-40-3
Synonyms
SMILESCOCCOCCOCCOCC[N+]1=C(/C=C/C=C/C=C/C=C2N(CCOCCOCCOCCOCCN=[N+]=[N-])C3=C(C=CC=C3)C/2(C)C)C(C)(C)C4=C1C=CC=C4.[Cl-]
Biological Activity
DescriptionN-(m-PEG4)-N'-(azide-PEG4)-Cy7 is a PEG-based linker designed for use in PROTAC (proteolysis targeting chimeras) synthesis. This compound features an azide functional group, allowing it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing partners, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups. Its biological activity in forming stable linkages facilitates targeted proteolysis research applications, making it a valuable tool for molecular biology and drug development studies.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.