Product Data Sheet
Propargyl-PEG5-1-o-(b-cyanoethyl-n,n-diisopropyl)phosphoramidite
Catalog No. A83408
Propargyl-PEG5-1-o-(b-cyanoethyl-n,n-diisopropyl)phosphoramidite functions as a PEG-based linker for protein degradation technologies, specifically PROTAC synthesis. This compound includes an alkyne functionality that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc), enabling efficient conjugation with azide-containing partners. It is suitable for applications in targeted protein degradation studies and offers versatility in the development of innovative therapeutic modalities.
Chemical Information
| Catalog Num | A83408 |
|---|---|
| M. Wt | 432.49 |
| Formula | C20H37N2O6P |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1682657-14-2 |
| Synonyms | |
| SMILES | C#CCOCCOCCOCCOCCOP(N(C(C)C)C(C)C)OCCC#N |
Biological Activity
| Description | Propargyl-PEG5-1-o-(b-cyanoethyl-n,n-diisopropyl)phosphoramidite functions as a PEG-based linker for protein degradation technologies, specifically PROTAC synthesis. This compound includes an alkyne functionality that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc), enabling efficient conjugation with azide-containing partners. It is suitable for applications in targeted protein degradation studies and offers versatility in the development of innovative therapeutic modalities. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
