Product Data Sheet
MS-PEG12-THP
Catalog No. A83485
MS-PEG12-THP is a polyethylene glycol (PEG)-based PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This linker facilitates the efficient conjugation of target proteins to E3 ubiquitin ligases, thereby enhancing the degradation of specific proteins in cellular contexts. Its applications include drug development and the study of targeted protein degradation mechanisms, making it a valuable tool in chemical biology and therapeutic research.
Chemical Information
| Catalog Num | A83485 |
|---|---|
| M. Wt | 708.85 |
| Formula | C30H60O16S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 552886-58-5 |
| Synonyms | |
| SMILES | O=S(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC1CCCCO1)(C)=O |
Biological Activity
| Description | MS-PEG12-THP is a polyethylene glycol (PEG)-based PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This linker facilitates the efficient conjugation of target proteins to E3 ubiquitin ligases, thereby enhancing the degradation of specific proteins in cellular contexts. Its applications include drug development and the study of targeted protein degradation mechanisms, making it a valuable tool in chemical biology and therapeutic research. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
