Product Data Sheet
Azido-PEG3-amide-C3-triethoxysilane
Catalog No. A83556
Azido-PEG3-amide-C3-triethoxysilane is a PEG-based linker designed for use in the synthesis of PROTACs, specifically targeting protein degradation pathways. This compound features an azide functional group that enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN-modified entities, making it a versatile tool for chemical biology applications in the development of targeted protein modulators.
Chemical Information
| Catalog Num | A83556 |
|---|---|
| M. Wt | 450.60 |
| Formula | C18H38N4O7Si |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2243566-43-8 |
| Synonyms | |
| SMILES | O=C(NCCC[Si](OCC)(OCC)OCC)CCOCCOCCOCCN=[N+]=[N-] |
Biological Activity
| Description | Azido-PEG3-amide-C3-triethoxysilane is a PEG-based linker designed for use in the synthesis of PROTACs, specifically targeting protein degradation pathways. This compound features an azide functional group that enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN-modified entities, making it a versatile tool for chemical biology applications in the development of targeted protein modulators. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
