Product Data Sheet

Fmoc-N-amido-PEG3-azide

Catalog No. A83643

main product photo
Fmoc-N-amido-PEG3-azide is a PEG-based linker designed for use in the synthesis of PROTACs, functioning primarily through click chemistry. This compound features an azide group that allows for efficient copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN-modified compounds, making it a versatile tool in chemical biology research and therapeutic development.
Chemical Information
Catalog NumA83643
M. Wt440.49
FormulaC23H28N4O5
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1172605-58-1
Synonyms
SMILESO=C(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)NCCOCCOCCOCCN=[N+]=[N-]
Biological Activity
DescriptionFmoc-N-amido-PEG3-azide is a PEG-based linker designed for use in the synthesis of PROTACs, functioning primarily through click chemistry. This compound features an azide group that allows for efficient copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN-modified compounds, making it a versatile tool in chemical biology research and therapeutic development.
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SHIPPING AND STORAGE
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