Product Data Sheet

TCO-PEG2-NHS ester

Catalog No. A83704

main product photo
TCO-PEG2-NHS ester is a PEG-based linker designed for use in the synthesis of PROTACs. This reagent features a TCO group capable of participating in an inverse electron demand Diels-Alder (iEDDA) reaction with tetrazine-containing molecules, facilitating targeted protein degradation applications. Its unique properties make it an essential component for researchers investigating protein modulation through innovative PROTAC methodologies.
Chemical Information
Catalog NumA83704
M. Wt426.46
FormulaC20H30N2O8
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2250217-33-3
Synonyms
SMILESO=C(NCCOCCOCCC(ON1C(CCC1=O)=O)=O)OC2CC/C=C\CCC2
Biological Activity
DescriptionTCO-PEG2-NHS ester is a PEG-based linker designed for use in the synthesis of PROTACs. This reagent features a TCO group capable of participating in an inverse electron demand Diels-Alder (iEDDA) reaction with tetrazine-containing molecules, facilitating targeted protein degradation applications. Its unique properties make it an essential component for researchers investigating protein modulation through innovative PROTAC methodologies.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.