Product Data Sheet
Azido-PEG7-t-butyl ester
Catalog No. A83713
Azido-PEG7-t-butyl ester is a PEG-based linker designed for the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound features an azide group that enables efficient click chemistry through copper-catalyzed azide-alkyne cycloaddition (CuAAC) with alkyne-containing molecules. Additionally, Azido-PEG7-t-butyl ester can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with compounds featuring DBCO or BCN groups, making it a versatile tool in targeted protein degradation research. Its application in the development of PROTACs facilitates the modulation of protein levels, thus advancing studies in cellular biology and therapeutic strategies.
Chemical Information
| Catalog Num | A83713 |
|---|---|
| M. Wt | 479.56 |
| Formula | C21H41N3O9 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2596867-40-0 |
| Synonyms | |
| SMILES | O=C(CCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])OC(C)(C)C |
Biological Activity
| Description | Azido-PEG7-t-butyl ester is a PEG-based linker designed for the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound features an azide group that enables efficient click chemistry through copper-catalyzed azide-alkyne cycloaddition (CuAAC) with alkyne-containing molecules. Additionally, Azido-PEG7-t-butyl ester can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with compounds featuring DBCO or BCN groups, making it a versatile tool in targeted protein degradation research. Its application in the development of PROTACs facilitates the modulation of protein levels, thus advancing studies in cellular biology and therapeutic strategies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
