Product Data Sheet

m-PEG8-O-alkyne

Catalog No. A83751

main product photo
m-PEG8-O-alkyne is a PEG-based PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound features an alkyne functional group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc), enabling the effective conjugation of azide-containing molecules. m-PEG8-O-alkyne is instrumental in the development of targeted protein degradation strategies, making it valuable for probing cellular mechanisms and therapeutic interventions in various biological contexts.
Chemical Information
Catalog NumA83751
M. Wt422.51
FormulaC20H38O9
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.880081-81-2
Synonyms
SMILESCOCCOCCOCCOCCOCCOCCOCCOCCOCC#C
Biological Activity
Descriptionm-PEG8-O-alkyne is a PEG-based PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound features an alkyne functional group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc), enabling the effective conjugation of azide-containing molecules. m-PEG8-O-alkyne is instrumental in the development of targeted protein degradation strategies, making it valuable for probing cellular mechanisms and therapeutic interventions in various biological contexts.
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