Product Data Sheet
Pyrene-amido-PEG4-CH2CH2COOH
Catalog No. A83785
Pyrene-amido-PEG4-CH2CH2COOH is a PEGylated linker designed for use in PROTAC (proteolysis-targeting chimera) synthesis. This compound facilitates the assembly of PROTACs by connecting a targeting moiety to an E3 ligase, promoting ubiquitin-mediated degradation of specific proteins. Its unique structural properties enhance solubility and cellular uptake, making it suitable for exploring targeted protein degradation in various biological research contexts.
Chemical Information
| Catalog Num | A83785 |
|---|---|
| M. Wt | 495.56 |
| Formula | C28H33NO7 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1817735-34-4 |
| Synonyms | |
| SMILES | O=C(O)CCOCCOCCOCCOCCNC(C1=C2C=CC3=C4C2=C(CC=C4CC=C3)C=C1)=O |
Biological Activity
| Description | Pyrene-amido-PEG4-CH2CH2COOH is a PEGylated linker designed for use in PROTAC (proteolysis-targeting chimera) synthesis. This compound facilitates the assembly of PROTACs by connecting a targeting moiety to an E3 ligase, promoting ubiquitin-mediated degradation of specific proteins. Its unique structural properties enhance solubility and cellular uptake, making it suitable for exploring targeted protein degradation in various biological research contexts. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
