Product Data Sheet

N-(m-PEG4)-N'-(azide-PEG4)-Cy3

Catalog No. A83793

main product photo
N-(m-PEG4)-N'-(azide-PEG4)-Cy3 is a PEG-based linker designed for use in the synthesis of PROTAC (Proteolysis Targeting Chimeras). This molecule features an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing substrates, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN functionalities. Its efficient coupling capabilities make it valuable for advancing research in targeted protein degradation and the development of therapeutic modalities.
Chemical Information
Catalog NumA83793
M. Wt800.42
FormulaC42H62ClN5O8
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2107273-38-9
Synonyms
SMILESCC1(C)C(/C=C/C=C2N(CCOCCOCCOCCOCCN=[N+]=[N-])C3=C(C=CC=C3)C/2(C)C)=[N+](CCOCCOCCOCCOC)C4=C1C=CC=C4.[Cl-]
Biological Activity
DescriptionN-(m-PEG4)-N'-(azide-PEG4)-Cy3 is a PEG-based linker designed for use in the synthesis of PROTAC (Proteolysis Targeting Chimeras). This molecule features an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing substrates, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN functionalities. Its efficient coupling capabilities make it valuable for advancing research in targeted protein degradation and the development of therapeutic modalities.
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SHIPPING AND STORAGE
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