Product Data Sheet
Active-mono-sulfone-PEG8-acid
Catalog No. A83953
Active-mono-sulfone-PEG8-acid is a PEG-based linker designed for use in the development of PROTACs (Proteolysis Targeting Chimeras). This compound facilitates the conjugation of target ligands to E3 ligase components, thereby promoting targeted protein degradation. It offers significant potential in various biological research applications, including drug discovery and therapeutic development, by optimizing the spatial arrangement for effective and selective ubiquitination.
Chemical Information
| Catalog Num | A83953 |
|---|---|
| M. Wt | 767.88 |
| Formula | C37H53NO14S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2055048-45-6 |
| Synonyms | |
| SMILES | O=C(O)CCOCCOCCOCCOCCOCCOCCOCCOCCNC(C1=CC=C(C(C(CS(=O)(C2=CC=C(C)C=C2)=O)=C)=O)C=C1)=O |
Biological Activity
| Description | Active-mono-sulfone-PEG8-acid is a PEG-based linker designed for use in the development of PROTACs (Proteolysis Targeting Chimeras). This compound facilitates the conjugation of target ligands to E3 ligase components, thereby promoting targeted protein degradation. It offers significant potential in various biological research applications, including drug discovery and therapeutic development, by optimizing the spatial arrangement for effective and selective ubiquitination. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
