Product Data Sheet
7-Bromoheptanoyl chloride
Catalog No. A84116
7-Bromoheptanoyl chloride serves as a chemical linker for the development of PROTAC (Proteolysis Targeting Chimera) agents, specifically in the synthesis of EGFR degrader 9. This compound facilitates targeted protein degradation by connecting the ligand to the E3 ligase, enabling the selective ubiquitination of the target protein. Its application in PROTAC technology supports advancements in therapeutic strategies against diseases associated with epidermal growth factor receptor (EGFR) dysregulation.
Chemical Information
| Catalog Num | A84116 |
|---|---|
| M. Wt | 227.53 |
| Formula | C7H12BrClO |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 50733-91-0 |
| Synonyms | |
| SMILES | BrCCCCCCC(Cl)=O |
Biological Activity
| Description | 7-Bromoheptanoyl chloride serves as a chemical linker for the development of PROTAC (Proteolysis Targeting Chimera) agents, specifically in the synthesis of EGFR degrader 9. This compound facilitates targeted protein degradation by connecting the ligand to the E3 ligase, enabling the selective ubiquitination of the target protein. Its application in PROTAC technology supports advancements in therapeutic strategies against diseases associated with epidermal growth factor receptor (EGFR) dysregulation. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
