Product Data Sheet

tert-Butyl 3,3-difluoro-4-((methylsulfonyloxy)methyl)piperidine-1-carboxylate

Catalog No. A84251

main product photo
tert-Butyl 3,3-difluoro-4-((methylsulfonyloxy)methyl)piperidine-1-carboxylate serves as a specialized PROTAC linker, facilitating the development of targeted protein degradation therapeutics. This compound enhances the stability and efficacy of PROTACs by promoting effective ternary complex formation between E3 ligases and target proteins. Its application in chemical biology underscores its importance in novel therapeutic strategies aimed at selectively degrading specific proteins involved in various diseases.
Chemical Information
Catalog NumA84251
M. Wt329.36
FormulaC12H21F2NO5S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1864060-27-4
Synonyms
SMILESO=C(OC(C)(C)C)N1CCC(COS(=O)(=O)C)C(F)(F)C1
Biological Activity
Descriptiontert-Butyl 3,3-difluoro-4-((methylsulfonyloxy)methyl)piperidine-1-carboxylate serves as a specialized PROTAC linker, facilitating the development of targeted protein degradation therapeutics. This compound enhances the stability and efficacy of PROTACs by promoting effective ternary complex formation between E3 ligases and target proteins. Its application in chemical biology underscores its importance in novel therapeutic strategies aimed at selectively degrading specific proteins involved in various diseases.
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