Product Data Sheet
Cbz-NH-PEG5-CH2COOH
Catalog No. A84265
Cbz-NH-PEG5-CH2COOH is a polyethylene glycol (PEG)-based PROTAC linker designed for the synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound facilitates the conjugation of target proteins to E3 ubiquitin ligases, promoting selective degradation pathways. Its hydrophilic properties enhance solubility and improve pharmacokinetic profiles, making it a valuable tool in targeted protein degradation research and drug development.
Chemical Information
| Catalog Num | A84265 |
|---|---|
| M. Wt | 429.46 |
| Formula | C20H31NO9 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1449390-66-2 |
| Synonyms | |
| SMILES | O=C(OCC1=CC=CC=C1)NCCOCCOCCOCCOCCOCC(O)=O |
Biological Activity
| Description | Cbz-NH-PEG5-CH2COOH is a polyethylene glycol (PEG)-based PROTAC linker designed for the synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound facilitates the conjugation of target proteins to E3 ubiquitin ligases, promoting selective degradation pathways. Its hydrophilic properties enhance solubility and improve pharmacokinetic profiles, making it a valuable tool in targeted protein degradation research and drug development. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
