Product Data Sheet
PROTAC AR Degrader-11
Catalog No. A84578
PROTAC AR Degrader-11 is a targeted degrader of the androgen receptor and androgen receptor splice variant-7, utilizing a proteolysis-targeting chimeric (PROTAC) approach. This compound exhibits significant cytotoxicity against prostate cancer cell lines, specifically CWR22RV1 and VCaP. PROTAC AR Degrader-11 is applicable in prostate cancer research, aiding investigations into androgen receptor modulation and degradation mechanisms.
Chemical Information
| Catalog Num | A84578 |
|---|---|
| M. Wt | 736.74 |
| Formula | C36H39F3N8O6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2798907-41-0 |
| Synonyms | |
| SMILES | O=C(COCCCCOC1=CC=C(C2CCN(CC2)C3=NN4C(CC3)=NN=C4C(F)(F)F)C=C1)NC5=CC=CC6=C5CN(C7C(NC(CC7)=O)=O)C6=O |
Biological Activity
| Description | PROTAC AR Degrader-11 is a targeted degrader of the androgen receptor and androgen receptor splice variant-7, utilizing a proteolysis-targeting chimeric (PROTAC) approach. This compound exhibits significant cytotoxicity against prostate cancer cell lines, specifically CWR22RV1 and VCaP. PROTAC AR Degrader-11 is applicable in prostate cancer research, aiding investigations into androgen receptor modulation and degradation mechanisms. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
