Product Data Sheet
PROTAC ER Degrader-10
Catalog No. A84615
PROTAC ER Degrader-10 is a selective PROTAC aimed at degrading estrogen receptors (ERs) within cancer cells. This compound exhibits significant efficacy in promoting targeted degradation of the ER, thereby disrupting cellular pathways linked to tumor growth and survival. Its primary application lies in cancer research, striving to elucidate mechanisms of ER-mediated signaling and provide insights into potential therapeutic strategies for estrogen-dependent malignancies.
Chemical Information
| Catalog Num | A84615 |
|---|---|
| M. Wt | 739.86 |
| Formula | C44H45N5O6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2504911-58-2 |
| Synonyms | |
| SMILES | OC1=CC=C([C@@](C2=CC=C(N3CCC(CC3)CN4CCN(C5=CC=C(C(N(C6C(NC(CC6)=O)=O)C7=O)=O)C7=C5)CC4)C=C2)([H])[C@@](C8=CC=CC=C8)([H])CO9)C9=C1 |
Biological Activity
| Description | PROTAC ER Degrader-10 is a selective PROTAC aimed at degrading estrogen receptors (ERs) within cancer cells. This compound exhibits significant efficacy in promoting targeted degradation of the ER, thereby disrupting cellular pathways linked to tumor growth and survival. Its primary application lies in cancer research, striving to elucidate mechanisms of ER-mediated signaling and provide insights into potential therapeutic strategies for estrogen-dependent malignancies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
