Product Data Sheet
TPKI-39
Catalog No. A84670
TPKI-39 is an inhibitor of DDR1, DDR2, and FLT1, demonstrating a human DDR1 IC50 of 380 nM and human DDR2 IC50 of 120 nM. It effectively inhibits enzymatic activity and autophosphorylation of DDR1 and DDR2, as well as FLT1 enzymatic activity, with an IC50 of 65 nM. This compound is useful for studies focused on the modulation of receptor tyrosine kinases and collagen-mediated signaling pathways.
Chemical Information
| Catalog Num | A84670 |
|---|---|
| M. Wt | 345.35 |
| Formula | C19H15N5O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1005781-50-9 |
| Synonyms | |
| SMILES | O=C(NC1=CC=CC(OC2=NN3C=CN=C3C=C2)=C1)NC4=CC=CC=C4 |
Biological Activity
| Description | TPKI-39 is an inhibitor of DDR1, DDR2, and FLT1, demonstrating a human DDR1 IC50 of 380 nM and human DDR2 IC50 of 120 nM. It effectively inhibits enzymatic activity and autophosphorylation of DDR1 and DDR2, as well as FLT1 enzymatic activity, with an IC50 of 65 nM. This compound is useful for studies focused on the modulation of receptor tyrosine kinases and collagen-mediated signaling pathways. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
