Product Data Sheet
DDR1-IN-4
Catalog No. A84673
DDR1-IN-4 is a selective inhibitor of Discoidin Domain Receptor 1 (DDR1), effectively blocking its autophosphorylation with an IC50 of 29 nM. This compound exhibits significantly lower activity against DDR2, with an IC50 of 1.9 μM. DDR1-IN-4 is utilized in research applications focusing on cell signaling, extracellular matrix interactions, and cancer biology, providing valuable insights into the role of DDR1 in various pathological conditions.
Chemical Information
| Catalog Num | A84673 |
|---|---|
| M. Wt | 565.34 |
| Formula | C23H20BrF3N6O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2125676-13-1 |
| Synonyms | |
| SMILES | O=C(NCC(F)(F)F)CN1C(C2(CCN(C(C3=CC=C(NN=C4)C4=N3)=O)CC2)C5=C1C=CC=C5Br)=O |
Biological Activity
| Description | DDR1-IN-4 is a selective inhibitor of Discoidin Domain Receptor 1 (DDR1), effectively blocking its autophosphorylation with an IC50 of 29 nM. This compound exhibits significantly lower activity against DDR2, with an IC50 of 1.9 μM. DDR1-IN-4 is utilized in research applications focusing on cell signaling, extracellular matrix interactions, and cancer biology, providing valuable insights into the role of DDR1 in various pathological conditions. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
