Product Data Sheet
DDR Inhibitor
Catalog No. A84676
DDR Inhibitor is a highly selective inhibitor of the discoidin domain receptors (DDRs), specifically demonstrating an IC50 of 3.3 nM for DDR2. Additionally, it exhibits a significant inhibitory effect on DDR1, with 53% inhibition at a concentration of 1.5 nM. This compound is valuable for investigating the role of DDRs in cellular processes and may have applications in cancer research and fibrosis studies.
Chemical Information
| Catalog Num | A84676 |
|---|---|
| M. Wt | 417.44 |
| Formula | C23H20FN5O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1644069-80-6 |
| Synonyms | |
| SMILES | O=C(C1=CN=C2C=CC=CN21)NC3=CC(CNC(NC4=CC=CC(F)=C4)=O)=CC=C3C |
Biological Activity
| Description | DDR Inhibitor is a highly selective inhibitor of the discoidin domain receptors (DDRs), specifically demonstrating an IC50 of 3.3 nM for DDR2. Additionally, it exhibits a significant inhibitory effect on DDR1, with 53% inhibition at a concentration of 1.5 nM. This compound is valuable for investigating the role of DDRs in cellular processes and may have applications in cancer research and fibrosis studies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
