Product Data Sheet
UniPR129
Catalog No. A84691
UniPR129 is a potent, orally active antagonist of Eph/ephrin interactions. It effectively inhibits the EphA2-ephrin-A1 interaction with an IC50 of 945 nM and a Ki of 370 nM. This compound has demonstrated the ability to inhibit angiogenesis and exhibits both antitumor and neuroprotective properties. UniPR129 is suitable for research applications in cancer and neurological disorders, including colorectal cancer and optic neuropathy.
Chemical Information
| Catalog Num | A84691 |
|---|---|
| M. Wt | 576.81 |
| Formula | C36H52N2O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1639159-47-9 |
| Synonyms | |
| SMILES | C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCC(N[C@H](CC(O)=O)CC3=CNC4=CC=CC=C34)=O)([H])[C@@]5([H])[C@]([C@@]6([C@](C[C@H](O)CC6)([H])CC5)C)([H])CC1 |
Biological Activity
| Description | UniPR129 is a potent, orally active antagonist of Eph/ephrin interactions. It effectively inhibits the EphA2-ephrin-A1 interaction with an IC50 of 945 nM and a Ki of 370 nM. This compound has demonstrated the ability to inhibit angiogenesis and exhibits both antitumor and neuroprotective properties. UniPR129 is suitable for research applications in cancer and neurological disorders, including colorectal cancer and optic neuropathy. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
