Product Data Sheet
Targefrin
Catalog No. A84694
Targefrin is a potent EphA2-targeting agent that functions as an antagonist. It exhibits high affinity for the EphA2 ligand-binding domain, with a dissociation constant of 21 nM and an IC50 value of 10.8 nM. Targefrin induces internalization and degradation of the EphA2 receptor in various pancreatic cancer cell lines, making it a valuable tool for research on cancer biology and therapeutic targeting of EphA2-related pathways.
Chemical Information
| Catalog Num | A84694 |
|---|---|
| M. Wt | 1700.94 |
| Formula | C85H116F3N19O15 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3031514-44-7 |
| Synonyms | |
| SMILES |
Biological Activity
| Description | Targefrin is a potent EphA2-targeting agent that functions as an antagonist. It exhibits high affinity for the EphA2 ligand-binding domain, with a dissociation constant of 21 nM and an IC50 value of 10.8 nM. Targefrin induces internalization and degradation of the EphA2 receptor in various pancreatic cancer cell lines, making it a valuable tool for research on cancer biology and therapeutic targeting of EphA2-related pathways. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
