Product Data Sheet
UniPR1447
Catalog No. A84696
UniPR1447 is a dual antagonist of EphA2 and EphB2, exhibiting an IC50 of 6.6 μM for the inhibition of the EphA2-ephrin-A1 interaction. This compound serves as a valuable tool in research focused on the role of Eph receptors in cellular processes such as angiogenesis, tumor progression, and neural development. Its application in studies targeting EphA2 and EphB2 signaling pathways contributes to understanding their implications in various diseases, making UniPR1447 a relevant reagent for therapeutic exploration.
Chemical Information
| Catalog Num | A84696 |
|---|---|
| M. Wt | 574.79 |
| Formula | C36H50N2O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1809170-68-0 |
| Synonyms | |
| SMILES | C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCC(N[C@H](CC(O)=O)CC3=CNC4=CC=CC=C34)=O)([H])[C@@]5([H])[C@@](CC1)([H])[C@@]6(C(C[C@H](CC6)O)=CC5)C |
Biological Activity
| Description | UniPR1447 is a dual antagonist of EphA2 and EphB2, exhibiting an IC50 of 6.6 μM for the inhibition of the EphA2-ephrin-A1 interaction. This compound serves as a valuable tool in research focused on the role of Eph receptors in cellular processes such as angiogenesis, tumor progression, and neural development. Its application in studies targeting EphA2 and EphB2 signaling pathways contributes to understanding their implications in various diseases, making UniPR1447 a relevant reagent for therapeutic exploration. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
